LIVE 0.5.1.1
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Controlled Substances

Follow the nurse's journal at Lakevale Sanctuary, investigate Dr. Khae's office, interrogation room and south-wing staff room, gain west-wing access, and recover the pure sample.

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Earlier source versions · See version & sources

Handshake

What to do

Map links are approximate objective references. They do not establish an entrance, floor or item surface.

  1. 1

    Investigate the nurse's accommodations at Lakevale Sanctuary.

    184, 141185, 141
  2. 2

    Search the nurse’s accommodations for hidden intel.

    Nurse’s Journal
    184, 141184, 141
  3. 3

    Read the nurse’s journal and report your findings.

    Nurse’s Journal
    184, 141
  4. 4

    Search Dr. Khae’s office for intel.

    184, 142
    1. 4.1

      Find any official documents.

    2. 4.2

      Find Dr. Khae’s personal notes.

  5. 5

    Search the interrogation room for intel.

    183, 142
  6. 6

    Search the south-wing staff room for any intel about Khae’s laboratory.

    183, 141
  7. 7

    Gain access to the west wing.

    183, 142183, 142
  8. 8

    Retrieve a pure sample and report back to Handshake.

    1. 8.1

      Find a pure sample inside Dr. Khae's laboratory.

      183, 142183, 142

    Then complete the objective

    Retrieve a pure sample and report back to Handshake.

Finish & hand in

  • Retrieve a pure sample and report back to Handshake.
  • Stay alive during the task.
Version, sources & details

The guide combines documented older builds and dated recordings. It is not verified in game for live patch 0.5.1.1. Loot, costs and times may have changed.

0.5.0 / cb4f600 (2026-10-22) · Sources checked 14 November 2026

Open source
All related map references (12)

Each map point shows its own meaning and precision.

Controlled Substances · Source objective reference 1 · 184, 141Controlled Substances · Source objective reference 2 · 185, 141Controlled Substances · Source objective reference 3 · 184, 141Controlled Substances · Source objective reference 4 · 184, 141Controlled Substances · Source objective reference 5 · 184, 141Controlled Substances · Source objective reference 6 · 184, 142Controlled Substances · Source objective reference 7 · 183, 142Controlled Substances · Source objective reference 8 · 183, 141Controlled Substances · Source objective reference 9 · 183, 142Controlled Substances · Source objective reference 10 · 183, 142Controlled Substances · Source objective reference 11 · 183, 142Controlled Substances · Source objective reference 12 · 183, 142

Not yet established

  • The reviewed text describes the mission goal, not a complete arrival-to-handover route.
  • Current-patch verification, sufficient map positions and visual step evidence are missing.
All sources & coverage